homepage  Publications

    2020

    31. Ynamide-Mediated Thionoester and Dithioester Syntheses

    Chaochao Yao; Jinhua Yang; Xiaobiao Lu; Shuyu Zhang; Junfeng Zhao*, Org. Lett. 2020. DOI: 10.1021/acs.orglett.0c02402


    30. Ynamide-Mediated Intermolecular Esterification

    Xuewei Wang,† Yang Yang,† Yongli Zhao, Sheng Wang, Wenchang Hu, Jinmei Li, Zihao Wang, Fengling Yang*, and Junfeng Zhao*, J. Org. Chem. 2020, 85, 6188-6194. (†X. Wang and Y. Yang contributed equally)


    29. Access to (Z)‑1,2-Endiamides and 1,1-Endiamides via a Base-Promoted Tandem Reaction

    Zhenming Zhang, Bei Fu, Hui Wang, Han Chen, Yongliang Tu, and Junfeng Zhao*, J. Org. Chem. 2020, 85, 5245-5254.


    28. Ynamide-Mediated Macrolactonization


    27. Transition-Metal-Free Approach to Polysubstituted Furans

    Changming You, Zhenming Zhang, Yongliang Tu, Hong Tang, Yuanfeng Wang, Da Long, and Junfeng Zhao*, J. Org. Chem. 2020, 85, 3902-3010.


    26. Site-Specific Incorporation of Multiple Thioamide Substitutions into a Peptide Backbone via Solid Phase Peptide Synthesis (Invited contribution for the Modern Peptide and Protein Chemistry special issue)

    Jinhua Yang, Changliu Wang, Chaochao Yao, Chunqiu Chen, Yafang Hu, Guifeng He, and Junfeng Zhao*, J. Org. Chem. 2020, 85, 1484-1494.


    2019

    25. Palladium-Catalyzed Hiyama Coupling of Benzylic Ammonium Salts via C−N Bond Cleavage

    Chunyu Han, Zhenming Zhang, Silin Xu, Kai, Wang, Kaiting Chen, and Junfeng Zhao*, J. Org. Chem. 2019. 84. 16308-16313. 


    24. Prof. Zhao was interviewed by Synform–Young Career Focus (from Prof. Matteo Zanda)


    23. Palladium-catalyzed Coupling of Terminal Alkynes with Benzyl Ammonium Salts

    Silin Xu, Zhenming Zhang, Chunyu Han, Wenkai Hu, Tiwen Xiao, Yanan Yuan, and Junfeng Zhao*, J. Org. Chem. 2019. 84. 12192-12197.


    22. Regio‐ and Stereoselective Hydrophosphorylation of Ynamides: A Facile Approach to (Z)‐β‐Phosphor‐Enamides

    Zhiyuan Peng,  Zhenming Zhang,  Xianzhu Zeng,  Yongliang Tu, and  Junfeng Zhao*, Adv. Syth. Catal. 2019. 19. 4489-4494.


    21. Transition-Metal-Free One-Step Synthesis of Ynamides

    Xianzhu Zeng,† Yongliang Tu,† ZhenmingZhang, Changming You, Jiao Wu, Zhiying Ye, and Junfeng Zhao*, J. Org. Chem. 2019, 84, 4458-4466. († X. Zeng and Y. Tu contributed equally)


    20. Ynamide‐Mediated Thiopeptide Synthesis

    Jinhua Yang,† Changliu Wang,† Silin Xu, and Junfeng Zhao*, Angew. Chem. Int. Ed. 2019, 58, 1382-1386. († J. Yang and C. Wang contributed equally)


    2018

    19. Regio- and Stereo-Selective Intermolecular Hydroamidation of Ynamides: An Approach to (Z)-Ethene-1,2-Diamides

    Zhiyuan Peng, Zhenming Zhang, Yongliang Tu, Xianzhu Zeng, and Junfeng Zhao*, Org. Lett. 2018, 20, 5688-5691.

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    18. Copper-Catalyzed Oxidative Functionalization of Benzylic C–H Bonds with Quinazoline 3-Oxides

    Liwen Fan, Zhenming Zhang, Tao Wang*, Qinjin Liang, and Junfeng Zhao*, Org. Chem. Front. 2018, 5, 2492-2495.

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    17. Synthesis of Triarylmethanes via Palladium-Catalyzed Suzuki Coupling of Trimethylammonium Salts and Arylboronic acids

    Zhenming Zhang, Hui Wang, Nianli Qiu, Yujing Kong, Wenjuan Zeng, Yongquan Zhang, and Junfeng Zhao*, J. Org. Chem. 2018, 83, 8710-8715.

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    16. Recent advances in enzyme-mediated peptide ligation (Invited review)

    Silin Xu, Zhenguang Zhao, and Junfeng Zhao*, Chin. Chem. Lett. 2018, 29, 1009-1016.

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    15. Palladium-Catalyzed Oxidative Cross-Coupling of Arylhydrazines and Arenethiols with Molecular Oxygen as the Sole Oxidant

    Changliu Wang, Zhenming Zhang, Yongliang Tu, Ying Li, Jiale Wu, and Junfeng Zhao*, J. Org. Chem. 2018, 83, 2389-2394.

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    14. Enantioselective Polyene Cyclization Catalyzed by a Chiral Brønsted Acid

    Liwen Fan,† Chunyu Han,† Xuerong Li,† Jiasheng Yao, Zhengning Wang, Chaochao Yao, Weihao Chen, Tao Wang and Junfeng Zhao*, Angew. Chem. Int. Ed. 2018, 57, 2115-2119. († L. Fan, C. Han and X. Li contributed equally)(highlighted by synfacts)

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    13. A Robust One-Step Approach to Ynamides

    Yongliang Tu,†  Xianzhu Zeng,†  Hui Wang, and Junfeng Zhao*,Org. Lett. 2018, 20, 280-283. († Y. Tu and X. Zeng contributed equally)

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    12. Recent developments in peptide ligation independent of amino acid side-chain functional group (Invited review)

    Jinhua Yang, and Junfeng Zhao*, Sci. China Chem. 2018, 61, 97-112.

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    2017

    11. Hypervalent Iodine-Mediated Oxidative Rearrangement of N–H Ketimines: An Umpolung Approach to Amides (invited contribution)

    Zhenguang Zhao, Zhiyuan Peng, Yongli Zhao, Hao Liu, Chongnan Li, and Junfeng Zhao*,  J. Org. Chem. 2017, 82, 11848-11853.

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    10. A regioselective approach to trisubstituted pyrazoles via palladium-catalyzed oxidative Sonogashira-carbonylation of arylhydrazines

    Yongliang Tu, Zhenming Zhang, Tao Wang*, Jiamei Ke, and Junfeng Zhao*, Org. Lett. 2017, 19, 3466-3469. 

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    9. Ynamide: a new coupling reagent for amide and peptide synthesis (Invited Synpacts)

    Long Hu, and Junfeng Zhao*, synlett. 2017, 28, 1663-1670.

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    8. Palladium-Catalyzed Oxidative Carbonylation of Aryl Hydrazines with CO and O2 at Atmospheric Pressure
    Yongliang Tu, Lin Yuan, Tao Wang*, Changliu Wang, Jiamei Ke, and Junfeng Zhao*, J. Org. Chem. 2017, 82, 4970-4976.

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    7. Palladium catalyzed Suzuki cross-coupling of benzyltrimethylammonium salts via C–N bond cleavage

    Tao Wang, Shuwu Yang, Silin Xu,Chunyu Han, Ge Guo,  and  Junfeng Zhao*,  RSC Adv. 2017, 7, 15805-15808

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    2016

    6. Ynamides as Racemization-Free Coupling Reagents for Amide and Peptide Synthesis

    Long Hu†, Silin Xu†, Zhenguang Zhao†, Yang Yang, Zhiyuan Peng, Ming Yang, Changliu Wang, and Junfeng Zhao*, J. Am. Chem. Soc. 2016, 138, 13135-13138. (†L.Hu., S. Xu. and Z. Zhao contributed equally) (highlighted by X-mol and Org. Chem. Portal)

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    5. Copper-catalyzed oxidative coupling between quinazoline 3-oxides and unactivated aldehydes:  an efficient  approach to functionalized quinazolines

    Liwen Fan, Tao Wang,* Ying Tian, Fei Xiong, Simei Wu, Qingjin Liang, and Junfeng Zhao*, Chem. Commun. 2016, 52, 5375-5378. 

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    4. Reaction between Azidyl Radical and Alkynes: A Straightforward Approach to NH-1, 2, 3-triazoles

    Long Hu, Christian Mück-Lichtenfeld, Tao Wang,* Guifeng He, Meng Gao, and Junfeng Zhao*, Chem. - Eur. J. 2016, 22, 911-915.

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    2015

    3. Oxidative Acylation of Sulfoximines with Methylarenes as Acyl Donor

    Zhenguang Zhao, Tao Wang,* Lin Yuan, Xingwang Jia, and Junfeng Zhao,* RSC Adv. 2015, 5, 75386-75389.

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    2. Direct oxidative amidation between methylarenes and amines in water

    Tao Wang, Lin Yuan, Zhenguang Zhao, Ailong Shao, Meng Gao, Yangfei Huang, Fei Xiong, Huali Zhang, and Junfeng Zhao,* Green Chem. 2015, 17, 2741-2744.

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    1. Oxidative Coupling between Methylarenes and Ammonia: A Direct Approach to Aromatic Primary Amides

    Zhenguang Zhao, Tao Wang,* Lin Yuan, Hu Xu, Fei Xiong, and Junfeng Zhao*. Adv. Synth.& Catal. 2015, 357, 2566-2570.

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     Before 2014

    18. Jun-Feng Zhao,* Xiao-Hong Zhang, Ying-Jie Ding, Yong-Sheng Yang, Xiao-Bao Bi, Chuan-Fa, Liu,* Facile Synthesis of Peptidyl Salicylaldehyde Esters and Its Use in Cyclic Peptide Synthesis Org. Lett. 2013, 15, 5182-5185.

     

    17. Chuan-Fa, Liu,* Jun-Feng Zhao, Patent, WO/2013/119184, PCT/SG2013/000052.

     

    16. Jun-Feng Zhao, Christian Mück-Lichtenfeld, Amido Studer,* Cooperative N-Heterocyclic Carbene (NHC) and Ruthenium Redox Catalysis: Oxidative Esterification of Aldehydes with Air as the Terminal Oxidant, Adv. Synth. & Catal. 2013, 355, 1098-1106.

     

    15. Jun-Feng Zhao, Boon-Hong Tan and Teck-Peng Loh,* In(III)-pybox complex catalyzed enantioselective Mukaiyama aldol reactions between polymeric or hydrated glyoxylates and enolsilanes derived from aryl, Chem. Sci. 2011, 2, 349-352.

     

    14. Ming-Kui Zhu, Jun-Feng Zhao, Teck-Peng Loh,* Palladium-Catalyzed C–C Bond Formation of Arylhydrazines with Olefins via Carbon–Nitrogen Bond Cleavage, Org. Lett. 2011, 13, 5714-5716.

     

    13. Jun-Feng Zhao, Boo-Hong Tan, Teguh-Budiono Tjan, and Teck-Peng Loh,*Enantioselective Carbonyl-Ene Reactions of Trifluoropyruvate in Ionic Liquid via a Recyclable Indium(III)-Pybox Complex, Adv. Synth. & Catal. 2010, 352, 2085-2088.

     

    12. Jun-Feng Zhao, Teguh-Budiono Tjan and Teck-Peng Loh,* Significant counterion effect of the In(III)–pybox complex in highly enantioselective carbonyl-ene reactions of ethyl glyoxylate, Tetrahedron Lett. 2010, 51, 5649-5652.

     

    11. Ming-Kui Zhu, Jun-Feng Zhao, Teck-Peng Loh,* Palladium-Catalyzed Oxime Assisted Intramolecular Dioxygenation of Alkenes with 1 atm of Air as the Sole Oxidant, J. Am. Chem. Soc. 2010, 132, 6284-6285.

     

    10. Jun-Feng Zhao, Teguh-Budiono Tjan, Boo-Hong Tan and Teck-Peng Loh,* Org. Lett. 2009, 11, 5714-5716 (Highlighted by SYNFACT, 2010, 2, 0206).

     

    9. Jun-Feng Zhao, and Teck-Peng Loh,* Acid-Catalyzed Intramolecular [2+2] Cycloaddition of Ene-allenones: Facile Access to Bicyclo[n.2.0] Frameworks, Angew. Chem. Int. Ed. 2009, 48, 7232-7235.

     

    8. Jun-Feng Zhao, Hoi-Yan Tsui, Pei-Jia Wu, Jun Lu and Teck-Peng Loh,* Highly Enantioselective Carbonyl-ene Reactions Catalyzed by In(III)−PyBox Complex J. Am. Chem. Soc. 2008, 130, 16492-16493. (Highlighted by SYNFACT, 2009, 2, 0187 and 2009, 3, 0283)

     

    7. Jun-Feng Zhao, Yu-Jun Zhao and Teck-Peng Loh,* Indium tribromide-promoted arene-terminated epoxy olefin cyclization, Chem. Commun. 2008, 1353-1355.

     

    6. Jun-Feng Zhao, Long He, Jun Jiang, Zhuo Tang, Lin-Feng Cun, Liu-Zhu Gong,* Organo-catalyzed highly diastereo- and enantio-selective direct aldol reactions in water, Tetrahedron Lett. 2008, 49, 3372-2275.

     

    5. Jun-Feng Zhao, Chang Xie, Sheng-Zhen Xu, Ming-Wu Ding,* Wen-Jing Xiao,* Iminophosphorane mediated efficient synthesis of new tricyclic 3,5-dihydro-1,2,3-triazolo[4,5-d]-1,2,4-triazolo[1,5-a]pyrimidin-9-ones Org. Bio. Chem. 2006, 4, 130-134.

     

    4. Jun-Feng Zhao, Chang Xie, Ming-Wu Ding,* Hong-Wu He,* Synthesis  2005, 15, 2544-2548

     

    3. Jun-Feng Zhao, Chang Xie, Ming-Wu Ding,* Hong-Wu He, A Selective Synthesis of 3,6-Dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-ones Chem. Lett.2005, 34, 1022-1023.

     

    2. Ming-Wu Ding,* Shen-Zhen Xu, Jun-Feng Zhao, Application of Bis(iminophosphorane) in Heterocyclic Synthesis:  New Entries to Symmetrically or Unsymmetrically Substituted Thieno[2,3-d:5,4-d‘]dipyr J. Org. Chem. 2004, 69, 8366-8371.

     

    1. Jun-Feng Zhao, Ming-Wu Ding,* J. World Pesticide 2004, 26, 14-17.




















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